top of page

10 Best Travel Destinations in South America

Updated: Oct 22, 2021


Planning a trip can be overwhelming, especially if you want to plan the ultimate South American escape! If your new year resolution includes traveling more, we have prepared a guide with the 10 best and most exciting travel destinations and experiences in South America for the year ahead. South America awaits!

1. Fascinating Brazilian Amazon Cruise

Why choose this destination? There is no way you visit South America and not adventure yourself into a memorable cruise of the Brazilian rainforest. Controlling about 60% of the Amazon Rainforest, Brazil is definitely the perfect destination for an Amazon cruise that will amaze your eyes and fill your soul with all the natural beauty that will surround you.

2. Luxury Adventure Cruise In The Galapagos Islands

Why choose this destination? if you are really into unforgettable cruises, you can add a luxury adventure cruise in the Galapagos Islands to your must-do list. These mesmerizing islands are among the best travel destinations in South America in 2020, and not only for their beauty and the amazing chance of swimming with the turtles.

When to go? From April to June it is warm, though wet, in the Galápagos Islands, ideal for swimming, snorkeling, and diving with turtles and sea lions. ⁠

Read more Best Time to Visit Ecuador’s Highlights: The Galapagos Island & The Amazon Jungle

Love underwater in Galapagos Island, Ecuador ❤️⁠Thanks @pelayosalinas for such a cute photo.⁠

3. Wild Escape in Patagonia, Argentina

Why choose this destination? With an impressive wild beauty and the possibility to indulge in different adrenaline-boosting activities, Patagonia deserves a place on this list. Whether you are a passionate hiker, you want to experience whale watching and walking among the charming Magellanic penguins in Puerto Madryn, or just explore and relax, a wild escape in Patagonia, Argentina is the answer.

Read More: 10 Reasons why you must add Patagonia to your Bucket List

Would you ever try to think about the size of a Glacier in the Southern Patagonian Ice Field? 📸 @coltonstiffler

4. An Adventure for Your Taste Buds: The Best Wines of Chile and Argentina

Why choose this destination? Chile and Argentina are great destinations for wine aficionados or curious travelers who want to learn all about wine while exploring the wineries and indulging in the best South American wine. And when you think about the delicious foods you can also taste while visiting these beautiful countries, you know your taste buds will run wild, and your vacation will be one of a kind.

Relax with this special sunset and enjoy the best wines at @vik_wine 📸from @sonny_loves_charlie

Read more Wine Destinations in South America to Tempt any Palate

5. Reach the End of the World: An Expedition Cruise to Antarctica

Why choose this destination? If you were wondering what kind of vacations will receive a lot of attention in the following year, having three types of amazing cruises on the best travel destinations in South America list gives you the answer. An expedition cruise to Antarctica is a fantastic choice for adrenaline seekers who want to reach the end of the world during their South American adventure.

Read more: Visit Antarctica – The Ultimate Guide for Planning Your Perfect Trip to Antarctica

6. Stroll the Vibrant Streets of Buenos Aires: Tango and Wine

Why choose this destination? Buenos Aires is the most amazing choice for city explorers who plan to visit South America. With an incredible restaurant scene, a bustling nightlife, and really friendly locals, Argentina’s vibrant heaven welcomes all travelers interested in discovering its amazing culture. Enjoying Tango and tasting delicious wine is an ideal combination.

7. Wine and Dine in Glorious Settings in Uruguay

Why choose this destination? Just like adventuring on idyllic cruises, tasting delicious wine and learning all about how it’s produced are great vacation activities in 2020. Though the Uruguay wine industry is still not huge, it is blossoming, giving connoisseurs and curious people the chance to see it grow, while exploring the unbeatable beauty and cuisine of Uruguay’s paradisiacal landscapes and charming cities. 

Read more: Why You Should Visit Uruguay on Your Next Trip to South America

8. Horseback Riding: Argentina’s Cozy Estancias for Horse and Nature Lovers

Why choose this destination? Estancias are part of the Argentine culture, and this is not only fantastic news for horse lovers but an incredible reason to add this to our best travel destinations in South America in 2020 list. Besides enjoying relaxing horseback rides on never-ending fields of beauty, an “estancia experience” also offer encounters with the traditions and history of the guanacos and the estancia.

Nibepo Aike Estancia in Patagonia Argentina. Whats Nibepo Aike means? 🤔 Aike means “place” in Tehuelche language, while Nibepo is formed with the first two letters of founder daughters’ nicknames. More than a century ago, a pioneer of Croatian origin found his place in the world in these limited lands. 12,000 hectares of mountains and natural grasslands with a privileged landscape on the shores of the South Arm of Lake Argentino. Today, after 4 generations, the stay and its activities remain in charge of the same family. .

9. Memorable Trekking Experiences: The W in Torres del Paine, Chile

Why choose this destination? There are so many places in South America that should be explored by foot, but there is no doubt that trekking the W in Torres del Paine in Chile is a must in 2020. The natural beauty, imposing mountains and green forests, the glaciers and lakes, the fauna, and the overall incredible vibe of Torres del Paine will blow your minds instantly.

Read more: All you need to know about the W Trekking Torres del Paine in Chile

Jagged peaks, massive glaciers, and pristine rivers define Patagonia. This destination, located between the borders of Chile 🇨🇱 and Argentina 🇦🇷 , is exactly what one would expect to see at the edge of the world. 📸 @jamesdorn_

10. Hikes to Remember: The Rainbow Mountain in Peru

Why choose this destination? Also known as Montana de Siete Colores, Montana de Colores, Vinicunca, and Winikunka, the Rainbow Mountain became a must-see in Peru, promising to soon be the second most visited attraction in the county, after the famous Machu Picchu. It’s definitely worth a visit, especially if you are a nature lover who knows how to enjoy a great hike.

Worth the hike! The stunning Vinicunca Mountains or Rainbow Mountains of Cusco, Peru 😍by @skipwithgrace

These are our 10 best travel destinations in South America in 2020, but as you probably imagine, there are many other incredible places and things to do, waiting for you in the beautiful South-American countries.

South America is a popular destination and advance planning is essential. Start by checking out our sample trips.

Maria Barciela Founding Partner & Director Across Argentina & South America Follow us on Instagram or facebook for more inspiration about Argentina & South America!

CONTACT US Start Planning Your Trip NowPlease enable JavaScript in your browser to complete this form.

Name *

Country *

Email *


We can call you if you want! Tell us a phone or whatsapp number and when is the best time to call you.

Comment or Message *

Tell us your trip plans! Destinations you want to visit, your travel dates, number of travelers, type of lodgments, etc.



Read our Latest Post

  1. Why You Should Choose a Glamping vacation at Patagonia Camp in Torres del Paine

  2. Chile Outdoor and Adventure Destinations

  3. Stories From Travelers: Trip to Torres del Paine, Patagonia Experience

  4. 5 reasons to visit Salta in Argentina on your next trip to South America

  5. Two Weeks Itinerary to Argentina for Nature Lovers: Ibera Wetlands, Iguazu Falls & The Northwest Tradition

About us! Clara & Maria

We believe South America is one of the most unforgettable places on earth – and we want you to help you fall in love with the continent just like we have. Born and raised in Buenos Aires, we founded Across South-America to help guests experience the ‘real’ South America – without compromising on comfort. A decade later, and Across South-America is a well-known boutique travel agency crafting outstanding vacations for couples, friends and families from all over the world. Our main point of difference is that we’re local experts. South America is our backyard. . Read More Let us show you the South America we know and love. Contact us!

#GuidesampTips #SouthAmerica


 We are Clara & Maria  

  • Pinterest
  • Instagram
  • Facebook


Our South America 
Travel Guide


_[TEMPLATE] Pinterest Pin (1).png

Use this guide to save you from endless hours of scrolling on the search page, looking for inspiration for your next trip to South America!

Unique experiences, dream boutique hotels, and estancias, the latest travel tips and suggested itineraries in South America, it’s all here waiting for you…


Our Travelers 


"Super Travel agency to South America" The women at Across South America did a fantastic job!! It may have taken 2 years to have our adventure ( because of COVID) but we did it! 



"Our month-long adventure was top-notch"

  The staff at Across South America were supporting us on a daily basis.   You cannot go wrong with Across South America. True custom travel.

Testimonials from our  travelers

Work together


OUR Latest Post

Sign up to be the first to receive our local tips & insights for your next trip to South America

Sisters and Partners at
Across South America

We founded 15 years ago Across South America, a female-founded and women-run Boutique Travel Agency to help travelers fall in love with South America just like we are.

bottom of page